›› LVEF - Left Ventricle Ejection Fraction


  In cardiovascular physiology, ejection fraction - Ef is the portion of blood pumped out of a ventricle
  with each heart strike. The term ejection fraction relates to both the right and left ventricles;
 One can speak equally of the left ventricular ejection fraction - LVEF and the right ventricular ejection
 fraction - RVEF. Without a specification,the expression Ejection Fraction refers specifically to that of
 the left ventricle.

 By classification, the amount of blood within a ventricle immediately before a contraction is known
 as the end-diastolic volume. Likewise, the volume of blood left in a ventricle at the end of contraction
 is end-systolic volume. The difference between end-diastolic and end-systolic amounts is the stroke volume,
 the volume of blood ejected with each beat. Ejection fraction - Ef is the fraction of the end-diastolic
 volume that is ejected with each beat; that is,it is stroke volume (SV) divided by end-diastolic volume (EDV):




Normal Values of LVEF

In a healthy 160-lb man, the SV is approximately 70 ml and the left ventricular EDV is 120 ml, calculating
an ejection fraction - LVEF of 70/120, or 0.58 (58%).

Right ventricular amount being approximately equal to those of the left ventricle, the ejection fraction
of the right ventricle is usually equivalent to that of the left ventricle within narrow limits.

Healthy individuals on average have ejection fractions between 50% and 65%. Though, normal values depend upon
the modality being used to calculate the ejection fraction. Please read E-book for more details on that subject.
Damage to the muscle of the heart - Cardiomyopathy, weakens the heart's capability to eject blood and as a result
reduces Ejection Fraction.

The ejection fraction is one of the most important predictors of diagnosis. People with extensively reduced
ejection fractions typically have poorer prognoses. However, as I am mentioning in my E-book low LVEF is not
necessarily a major factor in diagnosis and treatment of dilated cardiomyopathy.

Measurement of LVEF

Ejection Fraction is usually measured by echocardiography, in which the volumes of the heart's chambers are
measured during the cardiac phase. Ejection Fraction - LVEF can after that be obtained by dividing stroke
volume by end-diastolic volume as described above.

The most precise among commonly used methods of obtaining ejection fraction is cardiac MRI.
Also it could be measured by fast scan cardiac computed axial tomography (CT) imaging,
ventriculography, Gated SPECT, and the MUGA scan. A MUGA scan involves the injection of a radioisotope into
the blood and detecting its flow through the left ventricle.
The historical gold standard for the measurement of ejection fraction is ventriculography

Please check my E-book for more detailed interpretation of LVEF.





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